Sanger Institute

Sanger Institute

Hinxton, GB

Sequencing Informatics - Senior Bioinformatics Developer

£37,865-£45,817 / YEAR
Salary per annum £37,865 to £45,817 Working pattern Full Time/Flexible working considered Contract Type Permanent Contract Length Permanent Job Reference 84309

The Opportunity

We have an exciting opportunity for a Senior Software Developer with Bioinformatics experience to join the Sequencing Informatics Group at the Wellcome Sanger Institute. You will be join a team working to add value to our DNA Pipelines data products and will support the delivery and integration of informatics pipelines wrapping or adapting existing pipelines to work in our high throughput environment.

This is a customer-facing role and you will be responsible for fulfilling the customer requirements to agree pipelines that are both useful to them and practical for Sequencing Informatics to run.

About the Team:

The Sequencing Informatics group ensures that the harvesting, storage and analysis of DNA sequence information at the Sanger Institute is as swift and efficient as possible. To do this the team develops software to support the high-throughput data production activities of the DNA Pipelines Operations teams.

About you

The role will require experience of creating, amending and running bioinformatics/sequencing analysis pipelines using standard Bioinformatics pipleines such as Nextflow, Snakemake and Cromwell. The role also requires using, creating and amending QC in these pipelines. You will be able to programme in Python and/or Perl, able to reproduce example analysis and be comfortable in using shell, using batch processing systems, and using cloud compute.

Working with customers to agree pipelines which are both useful to them and practical for DNAP to run is essential to this role, therefore you must be comfortable with engaging with people across all levels and through all channels of communication (e-mail, face-to-face). You will be a logical and analytical thinker, able to plan, organise and schedule your own workload in line with priorities, working quickly to solve problems but ensuring quality and accuracy is maintained. You will also be someone who is keen to help others and willing to share information and improved ways of working in a team setting.

Essential Skills


  • Experience of creating, amending and running bioinformatics/sequencing analysis pipelines.
  • Experience of programming in Python and/or Perl.
  • Experience of using standard Bioinformatics pipeline frameworks e.g. NextFlow, SnakeMake, Cromwell.
  • Experience of using, and creating or amending, QC in such pipelines.
  • Comfortable using the shell, using batch processing systems, and using cloud compute.
  • Able to produce reproducible example analysis and reporting e.g. Jupyter notebook use.

Skills and Attributes:

  • Self-motivated with the ability to work in an independent manner under minimal supervision - capable of day-to-day direction of one’s own research.
  • Ability to work well within a team: keen to engage with tasks to help others, and to both take, assess and apply feedback from other team members, and to provide constructive feedback to others (most often by reviewing pull requests).
  • Good communication and interpersonal skills
  • Excellent organisation and problem-solving skills
  • Inclusive, personal and emphatic
  • Logical and analytical thinker
  • Able to work effectively ensuring customer satisfaction within agreed timelines
  • Comfortable engaging with customers, either remotely or face-to-face

Other information

Flexible Working

We appreciate the importance of achieving a healthy work-life balance and support this with a number of benefits, including a flexible working policy for those who may wish to apply to amend their working pattern or arrangement. We welcome applications for this position that are looking for flexible working, such as flexible start and finish times, and equal consideration will be given to individuals regardless of their working preferences.

Application Process:

Please apply with your CV and a cover letter outlining your suitability for the role addressing the criteria set out above and in the job description.

Closing date: 27 June 2021